💊 Med cost guide
How much does Simparica Trio cost?
Simparica Trio (sarolaner + moxidectin + pyrantel) is a combination parasiticide (flea/tick + heartworm + intestinal worms) from Zoetis, used for monthly all-in-one parasite prevention for dogs. Here's what it actually costs in the US — and how to pay less.
Typical monthly cost
$28–$45 / month
Effectively replaces separate flea/tick + heartworm purchases, so compare against the combined cost of those.
What you'll pay
| Typical price | Unit |
|---|---|
| $165–$270 | per 6-chew (6-month) pack |
GoodRx coupon low $223.81 for a mid-band 6-pack (~$37/month); smaller weight bands price lower, vet retail higher. Costco's member prescription program also lists it.
Label dosing (for cost context, not a recommendation): One weight-banded chew monthly per the public label.
Why it costs what it does
Simparica Trio comes as: monthly chew, weight-banded, given at home. A few things set the price:
- This one is already near the price floor for its category — generic competition keeps it cheap, and the bigger recurring line item is usually the monitoring visits, not the medication itself.
Cheaper alternatives to ask your vet about
Splitting coverage — generic-priced heartworm chew (ivermectin/pyrantel, ~$5-$9/month) plus a sale-priced flea/tick chew — often undercuts the all-in-one. Manufacturer rebates run seasonally.
Never switch, split, or stop a prescription on your own — bring these options up at your next visit and let your vet make the call for your pet.
Before you fill
Price-check before you buy
The same prescription can vary 2–3× between the vet's shelf, online pet pharmacies, and retail. A written prescription is yours to fill anywhere — vets are required to provide one on request.
Disclosure: Meow Howl may earn a commission if you buy through links on this page, at no extra cost to you. Commissions never influence our pricing research.
Help paying for Simparica Trio
- Zoetis Petcare Rewards — Best value if your pet is already on a Zoetis med long-term (Apoquel, Simparica Trio).
- Costco Member Prescription Program (CMPP) — Worth a price check on any expensive monthly med if you already hold a membership.
Sources & price verification
- GoodRx — coupon low $223.81 per 6-pack (accessed 2026-06-11)
- Costco Member Prescription Program — membership pricing channel (accessed 2026-06-11)
- Petco — 6-month-supply retail listing (accessed 2026-06-11)
How we verify these prices
Prices aggregated 2026-06-11 from public retailer listings (Chewy Rx, Petco, Heartland Vet Supply, EntirelyPets Rx, BudgetPetCare, PetBucket), GoodRx coupon pages, manufacturer pages, and 2026 vet-cost guides. Vet-administered injectables (Librela, Solensia, Cytopoint, Adequan loading) use published clinic-price surveys because the drug is not sold direct to consumers. Ranges are medication-only unless noted; exam/administration fees are flagged separately. Prices move — re-verify before publishing figures on a page, and show the per-item verified date.
Last verified: June 11, 2026 · Region: US · Currency: USD
