💊 Med cost guide
How much does Simparica Trio cost?
Simparica Trio (sarolaner + moxidectin + pyrantel) is a combination parasiticide (flea/tick + heartworm + intestinal worms) from Zoetis, used for monthly all-in-one parasite prevention for dogs. Here's what it actually costs in the US, and how to pay less.
Typical monthly cost
$28-$45 / month
Effectively replaces separate flea/tick + heartworm purchases, so compare against the combined cost of those.
What you'll pay
| Typical price | Unit |
|---|---|
| $165-$270 | per 6-chew (6-month) pack |
GoodRx coupon low $223.81 for a mid-band 6-pack (~$37/month); smaller weight bands price lower, vet retail higher. Costco's member prescription program also lists it.
Label dosing (for cost context, not a recommendation): One weight-banded chew monthly per the public label.
Why it costs what it does
Simparica Trio comes as: monthly chew, weight-banded, given at home. A few things set the price:
- This one is already near the price floor for its category, generic competition keeps it cheap, and the bigger recurring line item is usually the monitoring visits, not the medication itself.
Cheaper alternatives to ask your vet about
Splitting coverage, generic-priced heartworm chew (ivermectin/pyrantel, ~$5-$9/month) plus a sale-priced flea/tick chew, often undercuts the all-in-one. Manufacturer rebates run seasonally.
Never switch, split, or stop a prescription on your own, bring these options up at your next visit and let your vet make the call for your pet.
Before you fill
Price-check before you buy
The same prescription can vary 2-3× between the vet's shelf, online pet pharmacies, and retail. A written prescription is yours to fill anywhere, vets are required to provide one on request.
Disclosure: Meow Howl may earn a commission if you buy through links on this page, at no extra cost to you. Commissions never influence our pricing research.
Help paying for Simparica Trio
- Zoetis Petcare Rewards, Best value if your pet is already on a Zoetis med long-term (Apoquel, Simparica Trio).
- Costco Member Prescription Program (CMPP), Worth a price check on any expensive monthly med if you already hold a membership.
Sources & price verification
- GoodRx, coupon low $223.81 per 6-pack (accessed 2026-06-11)
- Costco Member Prescription Program, membership pricing channel (accessed 2026-06-11)
- Petco, 6-month-supply retail listing (accessed 2026-06-11)
How we verify these prices
Prices aggregated 2026-06-11 from public retailer listings (Chewy Rx, Petco, Heartland Vet Supply, EntirelyPets Rx, BudgetPetCare, PetBucket), GoodRx coupon pages, manufacturer pages, and 2026 vet-cost guides. Vet-administered injectables (Librela, Solensia, Cytopoint, Adequan loading) use published clinic-price surveys because the drug is not sold direct to consumers. Ranges are medication-only unless noted; exam/administration fees are flagged separately. Prices move, re-verify before publishing figures on a page, and show the per-item verified date.
Last verified: June 11, 2026 · Region: US · Currency: USD
