๐Ÿ’Š Med cost guide

How much does Adequan Canine cost?

Adequan Canine (polysulfated glycosaminoglycan (PSGAG)) is a disease-modifying osteoarthritis injectable from American Regent Animal Health, used for non-infectious degenerative joint disease (arthritis) in dogs. Here's what it actually costs in the US โ€” and how to pay less.

๐Ÿถ Dogs Last verified: June 11, 2026

Typical monthly cost

$20โ€“$350 / month

Loading month is the expensive one: a 50 lb dog uses ~8 mL across 8 injections (~$140 drug-only), more with clinic administration fees. Off-label maintenance of 1-2 injections/month runs $20-$90.

What you'll pay

Typical priceUnit
$87.49โ€“$175 per 5 mL vial (2-pack $174.98)

Heartland Vet Supply: $87.49 single vial, $174.98 two-pack; manufacturer restricts discounting.

Label dosing (for cost context, not a recommendation): Public label: 2 mg/lb intramuscularly twice weekly for up to 4 weeks (max 8 injections); many vets then use a lower off-label maintenance interval.

Why it costs what it does

Adequan Canine comes as: 100 mg/mL injectable, 5 mL vial; IM injection at clinic or owner-given at home if the vet teaches it. A few things set the price:

  • No generic competition at our last check, so the manufacturer effectively sets the price.

Cheaper alternatives to ask your vet about

Home administration (vet-taught) removes per-visit fees; generic PSGAG is not available in the US at verification. Oral NSAIDs are cheaper but work differently.

Never switch, split, or stop a prescription on your own โ€” bring these options up at your next visit and let your vet make the call for your pet.

Before you fill

Price-check before you buy

The same prescription can vary 2โ€“3ร— between the vet's shelf, online pet pharmacies, and retail. A written prescription is yours to fill anywhere โ€” vets are required to provide one on request.

Disclosure: Meow Howl may earn a commission if you buy through links on this page, at no extra cost to you. Commissions never influence our pricing research.

Help paying for Adequan Canine

See all 18 programs that help with pet med costs โ†’

Sources & price verification

  • Heartland Vet Supply โ€” $87.49/vial and $174.98/2-pack, fetched directly (accessed 2026-06-11)
  • GoodRx โ€” coupon availability (accessed 2026-06-11)
  • Chewy Rx โ€” retail listing and label dosing (accessed 2026-06-11)
How we verify these prices

Prices aggregated 2026-06-11 from public retailer listings (Chewy Rx, Petco, Heartland Vet Supply, EntirelyPets Rx, BudgetPetCare, PetBucket), GoodRx coupon pages, manufacturer pages, and 2026 vet-cost guides. Vet-administered injectables (Librela, Solensia, Cytopoint, Adequan loading) use published clinic-price surveys because the drug is not sold direct to consumers. Ranges are medication-only unless noted; exam/administration fees are flagged separately. Prices move โ€” re-verify before publishing figures on a page, and show the per-item verified date.

Last verified: June 11, 2026 ยท Region: US ยท Currency: USD

Disclaimer: Educational information, not veterinary advice. Dosing details below are quoted from public FDA label information for cost-estimation context only โ€” they are not dosing recommendations. Always verify with your veterinarian and the official product label. See our medical disclaimer.