๐ Med cost guide
How much does Adequan Canine cost?
Adequan Canine (polysulfated glycosaminoglycan (PSGAG)) is a disease-modifying osteoarthritis injectable from American Regent Animal Health, used for non-infectious degenerative joint disease (arthritis) in dogs. Here's what it actually costs in the US โ and how to pay less.
Typical monthly cost
$20โ$350 / month
Loading month is the expensive one: a 50 lb dog uses ~8 mL across 8 injections (~$140 drug-only), more with clinic administration fees. Off-label maintenance of 1-2 injections/month runs $20-$90.
What you'll pay
| Typical price | Unit |
|---|---|
| $87.49โ$175 | per 5 mL vial (2-pack $174.98) |
Heartland Vet Supply: $87.49 single vial, $174.98 two-pack; manufacturer restricts discounting.
Label dosing (for cost context, not a recommendation): Public label: 2 mg/lb intramuscularly twice weekly for up to 4 weeks (max 8 injections); many vets then use a lower off-label maintenance interval.
Why it costs what it does
Adequan Canine comes as: 100 mg/mL injectable, 5 mL vial; IM injection at clinic or owner-given at home if the vet teaches it. A few things set the price:
- No generic competition at our last check, so the manufacturer effectively sets the price.
Cheaper alternatives to ask your vet about
Home administration (vet-taught) removes per-visit fees; generic PSGAG is not available in the US at verification. Oral NSAIDs are cheaper but work differently.
Never switch, split, or stop a prescription on your own โ bring these options up at your next visit and let your vet make the call for your pet.
Before you fill
Price-check before you buy
The same prescription can vary 2โ3ร between the vet's shelf, online pet pharmacies, and retail. A written prescription is yours to fill anywhere โ vets are required to provide one on request.
Disclosure: Meow Howl may earn a commission if you buy through links on this page, at no extra cost to you. Commissions never influence our pricing research.
Help paying for Adequan Canine
- Costco Member Prescription Program (CMPP) โ Worth a price check on any expensive monthly med if you already hold a membership.
- The Pet Fund โ The right fit for chronic-condition medication costs; wrong fit for emergencies.
Sources & price verification
- Heartland Vet Supply โ $87.49/vial and $174.98/2-pack, fetched directly (accessed 2026-06-11)
- GoodRx โ coupon availability (accessed 2026-06-11)
- Chewy Rx โ retail listing and label dosing (accessed 2026-06-11)
How we verify these prices
Prices aggregated 2026-06-11 from public retailer listings (Chewy Rx, Petco, Heartland Vet Supply, EntirelyPets Rx, BudgetPetCare, PetBucket), GoodRx coupon pages, manufacturer pages, and 2026 vet-cost guides. Vet-administered injectables (Librela, Solensia, Cytopoint, Adequan loading) use published clinic-price surveys because the drug is not sold direct to consumers. Ranges are medication-only unless noted; exam/administration fees are flagged separately. Prices move โ re-verify before publishing figures on a page, and show the per-item verified date.
Last verified: June 11, 2026 ยท Region: US ยท Currency: USD